Malaria is spread by Anopheles mosquito by the bites of parasites infected female mosquito. The main caused of malaria in human is Plasmodium falciparum and Plasmodium vivax. Malaria is a well-known as an acute febrile illness. The severe infection may lead to death without promptly treatment, but this disease can be prevented and curable. Common symptoms of malaria include fever and flu-like illness, shaking chills, headache, muscle aches, nausea, and vomiting. The symptoms begin 10 days to 14 days after the bite from the infected mosquitoes. According to World Health Organization (WHO), 247 million cases of malaria in 2021 occurred globally.